Table 1 List of synergic food supplements and its benefits of human health

1

Calcium and vitamin D

Prevention of colorectal neoplasia [42], lowered risk of fracture [43]

2

Vitamin A, vitamin A plus zinc, and multiple micronutrients

Improves anemia [44]

3

Extra virgin olive oil and apple-enriched dark chocolate

Improves endothelial function [45]

4

Vitamins D and K

Increased bone mineral density, improves cardiovascular health, beneficial effects on endocrine and oxidative stress [46]

Calcium and selenium

Reduces risk of prostate, lung, and colorectal cancer [47]

5

Zinc and vitamin A

Improves vitamin A status [48], decrease the risk of non-ardia stomach cancer [48]

6

Magnesium and vitamin B₆

Relieves anxiety-related problems in premenopausal women [42]

7

Vitamins C and D and zinc

Improves immune functions and prevents infections [49]

8

Vitamin A and vitamin E

Enhances vitamin A intestinal absorption, increased antioxidant capabilities, protect against some forms of cancer, and support a healthier gut [50, 51]

9

Vitamin A and iron

Increases the bioavailability of pro-vitamin A carotenoids, including alpha-carotene, beta-carotene, and beta-cryptoxanthin [52]; increases iron absorption, especially non-heme iron [53]; reverse iron deficiency anemia [54]